Review of formulation and evaluation of self-micro emulsifying drug delivery system (SMEDDS)
نویسندگان
چکیده
منابع مشابه
Formulation and Characterization of Novel Self Micro Emulsifying Drug Delivery System of Glimepiride
The purpose of preparing Self microemulsifying drug delivery system in this work is to enhance the solubility and oral bioavailability of poorly water soluble drug, Glimepiride. SMEDDS are the isotropic mixture of surfactant, co-surfactant and oil incorporated with drug. In the aqueous media, gastro intestinal motility emulsification takes place. Glimepiride was undergone solubility studies in ...
متن کاملFormulation and in-vitro evaluation of self microemulsifying drug delivery system (SMEDDS) of Furosemide
Aim of the present investigation was to develop the Self Microemulsifying Drug Delivery System (SMEDDS) of Furosemide. Furosemide is Class IV molecule according to BCS (Biopharmaceutical Classification System), having low solubility and low permeability. Prepared optimized SMEDDS of Furosemide composed of CAPTEX 500 as oil and Cremophore EL as surfactant in 20:80 ratio. Optimized SMEDDS of Furo...
متن کاملSelf Micro Emulsifying Drug Delivery System - A Capsulization
The aim of the present work is to emphasize about the importance and to make a capsule review on self micro emulsifying drug delivery system. Oral route of drug administration has been the most prominent way of drug delivery system, because of its ability to prepare the formulation in an economical way, easy to administer, does not require any specific storage condition compared with parenteral...
متن کاملA Self-microemulsifying Drug Delivery System (smedds)
The oral delivery of lipophilic drugs presents a major challenge because of the low aqueous solubility of such compounds. Selfmicroemulsifying drug delivery systems (SMEDDSs) have gained exposure for their ability to increase solubility and bioavailability of poorly soluble drugs. SMEDDS, which are isotropic mixtures of oils, surfactants, solvents and co-solvents/surfactants, can be used for th...
متن کاملSelf-microemulsifying drug delivery system (SMEDDS) of vinpocetine: formulation development and in vivo assessment.
A new self-microemulsifying drug delivery system (SMEDDS) has been developed to increase the solubility, dissolution rate and oral bioavailability of vinpocetine (VIP), a poor water-soluble drug. The formulations of VIP-SMEDDS were optimized by solubility assay, compatibility tests, and pseudo-ternary phase diagrams analysis. The optimal ratio in the formulation of SMEDDS was found to be Labraf...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ScienceRise: Pharmaceutical Science
سال: 2020
ISSN: 2519-4852,2519-4844
DOI: 10.15587/2519-4852.2020.210825